Hemiespasmo facial tratado con Toxina Botulínica, experiencia de 10 años.

Authors

  • Armando Gutiérrez Clínica Las Condes
  • Gladys Del Peso Hospital Clínico Universidad de Chile.
  • Tania Gutiérrez Hospital Clínico Universidad de Chile. Servicio de Medicina Física y Rehabilitación.
  • Verónica Hitschfeld Hospital Clínico Universidad de Chile. Servicio de Medicina Física y Rehabilitación.
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Abstract

Between 1992 and 2002, 77 patients (11.4% women ard 28.6% men} with facial hemispasm were treated with periodic intramuscular injections of Botuline Toxine (TB) using a novel system of application created at our clinic. The evaluotion and follow up was made with a tour grade Scott scale modified by the authors. A total of 415 applications of TB were made. The average internal between admínistration for each patient was of 5 months {ranging between 2. 5 and 18 months). The initial evaluation showed that the muscles involved were the orbicularis oculi muscle in 54. 1% of the patients, a mixed predominance in 40. 5% and the cygomatic muscle in 5.4%. Grade 4 spasm was seen in the 41.3% (maximum deficit), grade 3 in 46. 7%, grade 2 in 6. 7% and grade 1 in 5.3% of the patients studied. The treatment was considered successful when grade O or 1 of the new sea/e was seen at the follow up 15 and 30 days after TB administration and partial response when there was a reduction of one degree in the scale during the same period of time. This was achieved in the 64. 5 and 100% of the patients respectively. Adverse effects seen were: drop of the labial comissure in 5,3%, palpebral ptosis in 1,6% and diplopía in 0,24% of the patients. We conclude that this new method of administration of BT in facial hemispasm has a greater lll- free interval and less adverse effects than those published previously in the literature.

Keywords:

Espasmo Hemifacial/tratamiento farmacológico, Toxinas Botulínicas Tipo A/uso terapéutico, Fármacos Neuromusculares/uso terapéutico