The Van der Woude syndrome (VWS), is characterized by the presence of fistulae orífices in the lower lip, in association with cleft lip and/or cleft palote. Great expression variability has been described with an autosomal dominant pattern of inheritance. lt has a frequency considered of 1x100. 000 new born olive in caucasian population, and corresponds to the 1-2% of the cases with cleft lip-palate. The case of new born of femenine sex is reported that presents lower lip pits and cleft lip and cleft
palote, his father was puf under surgery in childhood to correct lower lip-fistulae. A bibliographical revision of the described cases is provided in order to give importance to avoid subdiagnosis by the great expression variability and comments on mollecular studies of its association to the microdeletion 1 q 32-41 .
Keywords:
Labio Leporino/diagnóstico, Labio Leporino/terapia, Fisura del Paladar/diagn´´ostico, Fisura del Paladar/terapia, Anomalías Múltiples
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How to Cite
Salazar, M. P. ., Pardo, A. ., Villaseca, C. ., & Castillo T, S. . (2003). Síndrome de Van der Woude. Reporte de un caso clínico y revisión de la literatura . Revista Hospital Clínico Universidad De Chile, 14(4), pp. 315–9. https://doi.org/10.5354/2735-7996.2003.79310
