Nuevos conceptos génicos en diferenciación sexual humana

Authors

  • Rosa Andrea Pardo Hospital Clínico Universidad de Chile. Sección Genética. Departamento de Medicina.
  • Silvia Castillo. Hospital Clínico Universidad de Chile. Sección Genética. Departamento de Medicina.
Download

Abstract

Human sexual differentiation is a complex process that begins from undifferentiated gonads and conducts (poromesonephric and mesonephic) that posteriorly, under genic and hormonal stimulí, will constitute the mole and female reproductive system. Different gene mutotions, chromosomol oberrofions. hormonal índuction by androgens ond other teratogens con disturb the normal pathwoy. In the present article we review the genes that, according to the last investigations, have been involved in the normal human gonadal differentiation.

Keywords:

Diferenciación Sexual/genética, Procesos de Determinación del Sexo/genética