The use of high porfia/ oxygen pressure in arterial blood has been blamed tor gaseous microemboli, generotion of oxygen free radicals and end damage. In order to reduce the arterial oxygen pressure during cardiopulmonory bypass some institutions decreose the oxygen inspired pressure with on air/oxygen blender.
The purpose of this invesfigation was to assess the impoct of the blender on postoperotive complications of patients undergoing elective coronory artery bypass gratting using cordiopulmonary bypass. 50 palients were randomly assigned to two groups: patients in group 1 (n =24) were oxygenated with high F/O2 (100%) while patienfs in group 2 (n=26) were managed with low FiO2 (40 - 60%). Possible consequences of fhe fwo strafegies were evaluated by measuring time to extubation (p=0.89) , posfoperafive bleeding (p =0. 76), serum markers of liver damage (p=0.79) and serum creatinine (p=0.93).
The study suggest that the two strofegies employed to manage arterial oxygen pressure during
cardioplulmonory bypass hove no effect on post operative complicafions at leqst for the variables
evaluated.
Díaz, R., González, M. ., Álvarez, E. ., Lizama, C. ., Reyes, R. ., Figueroa, E. ., & Ávila, . L. . (2002). Efectos del uso del mezclador aire / oxígeno en morbilidad de cirugía coronaria con circulación extracorpórea (CEC). Revista Hospital Clínico Universidad De Chile, 13(2), pp. 143–7. https://doi.org/10.5354/2735-7996.2002.79674
