Crohn's disease is a chronic intestinal infl.ammatíon with symptoms pertaining to the gastrointestinal tract, from the mouth to the anus. There are also extraintestinal manifestations in about 25-30% of the patients and they are more common in the colonic disease, rather than when it affects the small bowel.
In this article we review different symptoms and signs of several organs affected, as the skin, joints, biliary tract, eyes, and the less common manifestations in other organs.
Many times several organs appear affected simultaneously.
Generally the course of the extraintestinal manifestations parallels that of the intestinal disease, both in crisis, remissions, and response to steroids.
Very often, however, extraintestinal manifestations in Crohn's disease and ulcerative colitis are more severe and precede those of the intestinal tract, and in the differential diagnosis both of these last conditions should be considered.
Valera, J. M. ., & Morales, A. . (2001). Manifestaciones extraintestinales de la enfermedad de Crohn. Revista Hospital Clínico Universidad De Chile, 12(3), pp. 185–91. https://doi.org/10.5354/2735-7996.2001.79761
