We studied vesicoureteral reflux (RVU) in 24 children with idirect radionuclide cystography using Tc99m-DTPA vs radiological uretrocystography (UCRx); 20 with prior urinary infection, 14 with Known RVU and 14 with congenital abnormalities. They were 54% females , mean age 6.9yo (6m-14yo). Lasix was used in 83%. We analyzed 48 ureteral units; 19 with RVU in UCRx; 5 were excluded because isotopic RVU was undetermined (important DTPA pyelocalicial retention) . The concordance was 86% with kappa 0.71. Sensitivity was 83% and specificity 87%. Ali RVU III and Iv were detected with DTPA; they were all during miction and 39% premictional. Their severity
presented 73% of correlation (kappa 0.53). There was no difference between relative renal function in 20 kidneys comparing Tc99m DTPA with DMSA. Concluding, indirect cystography allows to evaluate RVU and also renal/excretory function.
However, it is preferred to avoid this non invasive and low radiation technique if there is hydronephrosis.
Massardo , T., Bernal, M. ., González, P., Campos, J. ., Castro, V. ., Armijo, S. ., Concha, C., & Garcés, N. (1997). Estudio de reflujo vesicoureteral en niños mediante uso de Tc99m DTPA endovenoso. Revista Hospital Clínico Universidad De Chile, 1997(8), pp. 270–4. https://doi.org/10.5354/2735-7996.4.81243