Detectable serum prostate specific antigen {PSAJ affer radical prostatectomy greater than 0,4 ng/ml indicates recurrence of di sea se and treatment f ai/ure. We characterized PSA recurrence atter radical prostatectomy and identify predictors.
We retrospecüve/y reviewed the medica/ records of 99 patients with clinically localized prostate cancer who underwent radical prostatectomy between 1998 and 2001. We study associations between clinical {PSA, clinical stage] and pathological findings with biochembal recurrence.
The mean age at time of surgery was 64,07 years, a mean followup of 37,3 months. The biochembal recurrence \!\OS 34%. The T2 stage, PSA over 10 ng/ml, high grade Gleason score, positive surgical
margins, seminal vesicle involvement and capsular invasion were significant associated with biochemical recurrence.
This study allows us to conclude that preoperative {serum PSA leve/ greater than 1 O ng/ml, high grade Gleason score, positive digital rectal examination} and postoperative {pathological findings} were predictive of biochemical recurrence in patients underwent radical prostatectcmy f or prostate cancer following.
Keywords:
Recurrencia Local de Neoplasia, Prostatectomía, Antígeno Prostático Específico, Neoplasias de la Próstata, Chile/epidemiología
Ossandón S, E. ., Cabezas C, J. ., Ledezma R, R. ., Mira O, M. ., & Sepúlveda A, I. . (2004). Seguimiento bioquímico de 99 pacientes sometidos a prostatectomía radical durante 3 años en el Hospital Clínico de la Universidad de Chile. Revista Hospital Clínico Universidad De Chile, 15(2), pp. 133–7. https://doi.org/10.5354/2735-7996.2004.79256
